Overexpressing corticotropin-releasing hor- mone (CRH) in the primate amygdala increases anxious temperament and alters its neural circuit
نویسندگان
چکیده
Cite this article as: Ned H Kalin, Andrew S Fox, Rothem Kovner, Marissa K Riedel, Eva M Fekete, Patrick H Roseboom, Do P M Tromp, Benjamin P Grabow, Miles E Olsen, Ethan K Brodsky, Daniel R. McFarlin, Andrew L Alexander, Marina E Emborg, Walter F Block, Julie L Fudge, Jonathan A Oler, Overexpressing corticotropin-releasing hormone (CRH) in the primate amygdala increases anxious temperament and alters its neural circuit, Biological Psychiatry, http://dx. doi.org/10.1016/j.biopsych.2016.01.010
منابع مشابه
Overexpressing Corticotropin-Releasing Factor in the Primate Amygdala Increases Anxious Temperament and Alters Its Neural Circuit.
BACKGROUND Nonhuman primate models are critical for understanding mechanisms underlying human psychopathology. We established a nonhuman primate model of anxious temperament (AT) for studying the early-life risk to develop anxiety and depression. Studies have identified the central nucleus of the amygdala (Ce) as an essential component of AT's neural substrates. Corticotropin-releasing factor (...
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